SSRI Antidepressant Use During Pregnancy

Women taking SSRI’s (Selective Serotonin Reuptake Inhibitors) during pregnancy may increase the potential risk their newborn has congenital anomalies, neonatal withdrawal syndrome, and a rare heart and lung condition known as “Persistent Pulmonary Hypertension of newborns” (PPHN).

A population based cohort study from 1996 through 2007, used logistic regression to estimate relative risks of stillbirth, neonatal death, and postneonatal death associated with SSRI use during pregnancy. The study took maternal characteristics and previous psychiatric hospitalization into account.

The results of the study showed that, women exposed to an SSRI during pregnancy presented with higher rates of stillbirths, and postneonatal deaths than those who did not. With a total of 1,633,877 singleton birth in the study, 6054 were stillbirths, 3609 were neonatal deaths and 1578 were postneonatal deaths. However, in multivariable models, SSRI use was not associated with stillbirth, neonatal death, or postneonatal death. Estimates were further reduced when classified by previous hospitalization for psychiatric disease. Adjusting the operational research for stillbirths in women with psychiatric disease, and for those who had not been previously hospitalized.

In conclusion, the study found that, among women with singleton births, there was no significant association between use of SSRI’s during pregnancy, and the risk of stillbirth, neonatal mortality, or postneonatal mortality.

SSRI’s are marketed under various brand and generic drug names:

Generic Names:

  • Citalopram
  • Escitalopram
  • Fluoxetine
  • Fluvoxamine
  • Paroxetine
  • Sertraline
  • Vilazodone

Brand Names:

  • Celexa
  • Lexapro
  • Prozac, Sarafem, Symbyax
  • Luvox, Luvox CR
  • Paxil, Paxil CR, Pexeva
  • Zoloft
  • Viibryd

If you or a loved one has suffered injury or death due to a defective or dangerous pharmaceutical, you may have a right to compensation for your injuries.  The Maher Law Firm and Frank Eidson Attorney At Law would like to help.  We invite you to contact our trial tested dangerous drug attorneys today.

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